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Tissue-wide metabolomics reveals wide impact of gut microbiota on mice metabolite composition.

WP4 - Big data analysis of the gut microbiome, WP7 - Dissemination, Exploitation and Communication

Abstract (Expand)

The essential role of gut microbiota in health and disease is well recognized, but the biochemical details that underlie the beneficial impact remain largely undefined. To maintain its stability, ...

Authors: I. Zarei, V. M. Koistinen, M. Kokla, A. Klavus, Ambrin Farizah Babu, M. Lehtonen, S. Auriola, K. Hanhineva

Date Published: 2nd Sep 2022

Journal: Sci Rep

PubMed ID: 36056162

Citation: Sci Rep. 2022 Sep 2;12(1):15018. doi: 10.1038/s41598-022-19327-w.

Created: 22nd Nov 2022 at 10:26

Risk assessment with gut microbiome and metabolite markers in NAFLD development.

WP4 - Big data analysis of the gut microbiome, WP7 - Dissemination, Exploitation and Communication

(Show All)

Abstract (Expand)

A growing body of evidence suggests interplay between the gut microbiota and the pathogenesis of nonalcoholic fatty liver disease (NAFLD). However, the role of the gut microbiome in early detection of ...

Authors: Howell Leung, X. Long, Y. Ni, L. Qian, Manos Nychas, Sara Leal Siliceo, Dennis Pohl, K. Hanhineva, Y. Liu, A. Xu, H. B. Nielsen, E. Belda, K. Clement, R. Loomba, H. Li, W. Jia, G. Panagiotou

Date Published: 8th Jun 2022

Journal: Sci Transl Med

PubMed ID: 35675435

Citation: Sci Transl Med. 2022 Jun 8;14(648):eabk0855. doi: 10.1126/scitranslmed.abk0855. Epub 2022 Jun 8.

Created: 22nd Nov 2022 at 09:47

Physical Activity and Dietary Composition Relate to Differences in Gut Microbial Patterns in a Multi-Ethnic Cohort-The HELIUS Study.

WP4 - Big data analysis of the gut microbiome, WP7 - Dissemination, Exploitation and Communication

Abstract (Expand)

Physical activity (PA) at recommended levels contributes to the prevention of non-communicable diseases, such as atherosclerotic cardiovascular disease (asCVD) and type 2 diabetes mellitus (T2DM). Since ...

Authors: Veera Houttu, Ulrika Boulund, M. Nicolaou, A. G. Holleboom, A. Grefhorst, H. Galenkamp, B. J. van den Born, K. Zwinderman, M. Nieuwdorp

Date Published: 9th Dec 2021

Journal: Metabolites

PubMed ID: 34940616

Citation: Metabolites. 2021 Dec 9;11(12). pii: metabo11120858. doi: 10.3390/metabo11120858.

Created: 22nd Nov 2022 at 09:52

Decreased Abundance of Akkermansia muciniphila Leads to the Impairment of Insulin Secretion and Glucose Homeostasis in Lean Type 2 Diabetes.

WP4 - Big data analysis of the gut microbiome

Abstract (Expand)

Although obesity occurs in most of the patients with type 2 diabetes (T2D), a fraction of patients with T2D are underweight or have normal weight. Several studies have linked the gut microbiome to ...

Authors: J. Zhang, Y. Ni, L. Qian, Q. Fang, T. Zheng, M. Zhang, Q. Gao, Y. Zhang, J. Ni, X. Hou, Y. Bao, P. Kovatcheva-Datchary, A. Xu, H. Li, G. Panagiotou, W. Jia

Date Published: 5th Jun 2021

Journal: Adv Sci (Weinh)

PubMed ID: 34085773

Citation: Adv Sci (Weinh). 2021 Aug;8(16):e2100536. doi: 10.1002/advs.202100536. Epub 2021 Jun 4.

Created: 22nd Nov 2022 at 09:37

The role of the gut microbiome and exercise in non-alcoholic fatty liver disease.

WP2 - Human cohorts and mice models, WP4 - Big data analysis of the gut microbiome

Abstract (Expand)

In recent years, the human gut microbiome has been found to influence a multitude of non-communicable diseases such as cardiovascular disease and metabolic syndrome, with its components type 2 diabetes ...

Authors: Veera Houttu, Ulrika Boulund, A. Grefhorst, M. R. Soeters, S. J. Pinto-Sietsma, M. Nieuwdorp, A. G. Holleboom

Date Published: 25th Sep 2020

Journal: Therap Adv Gastroenterol

PubMed ID: 32973925

Citation: Therap Adv Gastroenterol. 2020 Sep 15;13:1756284820941745. doi: 10.1177/1756284820941745. eCollection 2020.

Created: 29th Mar 2021 at 10:09

Gut Microbiome Fermentation Determines the Efficacy of Exercise for Diabetes Prevention.

WP4 - Big data analysis of the gut microbiome

Abstract (Expand)

Exercise is an effective strategy for diabetes management but is limited by the phenomenon of exercise resistance (i.e., the lack of or the adverse response to exercise on metabolic health). Here, in ...

Authors: Y. Liu, Y. Wang, Y. Ni, C. K. Y. Cheung, K. S. L. Lam, Y. Wang, Z. Xia, D. Ye, J. Guo, M. A. Tse, G. Panagiotou, A. Xu

Date Published: 7th Jan 2020

Journal: Cell Metab

PubMed ID: 31786155

Citation: Cell Metab. 2020 Jan 7;31(1):77-91.e5. doi: 10.1016/j.cmet.2019.11.001. Epub 2019 Nov 27.

Created: 29th Mar 2021 at 10:08

Mining, analyzing, and integrating viral signals from metagenomic data.

WP4 - Big data analysis of the gut microbiome

Abstract (Expand)

BACKGROUND: Viruses are important components of microbial communities modulating community structure and function; however, only a couple of tools are currently available for phage identification and ...

Authors: T. Zheng, J. Li, Y. Ni, K. Kang, M. A. Misiakou, L. Imamovic, B. K. C. Chow, A. A. Rode, P. Bytzer, M. Sommer, G. Panagiotou

Date Published: 19th Mar 2019

Journal: Microbiome

PubMed ID: 30890181

Citation: Microbiome. 2019 Mar 19;7(1):42. doi: 10.1186/s40168-019-0657-y.

Created: 29th Mar 2021 at 10:07