Projects

Overall management of the project and communication with the EC.

Objectives: Investigate the association between gut microbiota and NAFLD using a biobank from a cross-sectional and prospective study. Explore the predictive role of baseline gut microbiota for the prognosis of NAFLD. Compare the clinical effects under different intensity of exercise. Explore the role of gut microbiota in progression of NAFLD. Explore the mechanisms of certain key functional strains in the NAFLD improvement.

Objectives: Explore the predictive role of cytokines like adiponectin and the ratio of adiponectin for the prognosis of NAFLD. Identify the mechanisms of exercise-responsive gut microbiota mediated improvement in NAFLD.

Objectives: Explore the association between gut microbiota, community diversity, structure and function, host metabolic phenotype and metabolic pathways. Model the association between microbial communities and metabolic disease state, by integrating meta-omic datasets in novel ways. Develop a framework for estimating microbial persistence and colonisation probabilities (MPCP) in the human gut microbiome from longitudinal data. Develop a computational pipeline for identifying bacterial gene clusters
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Objectives: To provide to all 15 ESRs involved a structured, interdisciplinary and inter-sectoral training program, supporting and supplementing activities in the research projects. The main objectives are to solve cross-disciplinary problems, and provide network-wide, local and external training to the ESRs, including secondments to partners in academia and industrial sectors, workshops, summer schools, and dissemination and outreach activities. To train ESRs in transferable skills (entrepreneurship,
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Objectives: To ensure a successful dissemination, exploitation and communication of the project results and scientific advancements, as well as increasing awareness in the general public of the benefits and need for new scientists.

Objectives: To make BestTreat research data findable, accessible, interoperable and re-usable (FAIR).