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Dietary Interventions in Patients With Non-alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis.
WP7 - Dissemination, Exploitation and Communication

Abstract (Expand)

Background: With no approved pharmacotherapy to date, the present therapeutic cornerstone for non-alcoholic fatty liver diseases (NAFLD) is a lifestyle intervention. Guidelines endorse weight loss ...

Authors: Veera Houttu, Susanne Csader, M. Nieuwdorp, A. G. Holleboom, Ursula Schwab

Date Published: 9th Aug 2021

Journal: Front Nutr

Role of microbiota and related metabolites in gastrointestinal tract barrier function in NAFLD.
WP7 - Dissemination, Exploitation and Communication

Abstract (Expand)

The Gastrointestinal (GI) tract is composed of four main barriers: microbiological, chemical, physical and immunological. These barriers play important roles in maintaining GI tract homeostasis. In the ...

Authors: M. V. Fernandez-Cantos, Johnson Lok, Valeria Iannone, H. El-Nezami, M. Kolehmainen, O. P. Kuipers

Date Published: 19th Jul 2021

Journal: Tissue Barriers

Decreased Abundance of Akkermansia muciniphila Leads to the Impairment of Insulin Secretion and Glucose Homeostasis in Lean Type 2 Diabetes.
WP7 - Dissemination, Exploitation and Communication

Abstract (Expand)

Although obesity occurs in most of the patients with type 2 diabetes (T2D), a fraction of patients with T2D are underweight or have normal weight. Several studies have linked the gut microbiome to ...

Authors: J. Zhang, Y. Ni, L. Qian, Q. Fang, T. Zheng, M. Zhang, Q. Gao, Y. Zhang, J. Ni, X. Hou, Y. Bao, P. Kovatcheva-Datchary, A. Xu, H. Li, G. Panagiotou, W. Jia

Date Published: 4th Jun 2021

Journal: Adv Sci (Weinh)

The role of the gut microbiome and exercise in non-alcoholic fatty liver disease.
WP2 - Human cohorts and mice models, WP4 - Big data analysis of the gut microbiome

Abstract (Expand)

In recent years, the human gut microbiome has been found to influence a multitude of non-communicable diseases such as cardiovascular disease and metabolic syndrome, with its components type 2 diabetes ...

Authors: Veera Houttu, Ulrika Boulund, A. Grefhorst, M. R. Soeters, S. J. Pinto-Sietsma, M. Nieuwdorp, A. G. Holleboom

Date Published: 25th Sep 2020

Journal: Therap Adv Gastroenterol

Gut Microbiome Fermentation Determines the Efficacy of Exercise for Diabetes Prevention.
WP4 - Big data analysis of the gut microbiome

Abstract (Expand)

Exercise is an effective strategy for diabetes management but is limited by the phenomenon of exercise resistance (i.e., the lack of or the adverse response to exercise on metabolic health). Here, in ...

Authors: Y. Liu, Y. Wang, Y. Ni, C. K. Y. Cheung, K. S. L. Lam, Y. Wang, Z. Xia, D. Ye, J. Guo, M. A. Tse, G. Panagiotou, A. Xu

Date Published: 7th Jan 2020

Journal: Cell Metab

Mining, analyzing, and integrating viral signals from metagenomic data.
WP4 - Big data analysis of the gut microbiome

Abstract (Expand)

BACKGROUND: Viruses are important components of microbial communities modulating community structure and function; however, only a couple of tools are currently available for phage identification and ...

Authors: T. Zheng, J. Li, Y. Ni, K. Kang, M. A. Misiakou, L. Imamovic, B. K. C. Chow, A. A. Rode, P. Bytzer, M. Sommer, G. Panagiotou

Date Published: 19th Mar 2019

Journal: Microbiome

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