1. Home
  2. Publications Index

Publications

FilterFilter and export
Does aerobic exercise reduce NASH and liver fibrosis in patients with non-alcoholic fatty liver disease? A systematic literature review and meta-analysis.
WP7 - Dissemination, Exploitation and Communication

Abstract (Expand)

Background: Exercise is an effective strategy for the prevention and regression of hepatic steatosis in patients with non-alcoholic fatty liver disease (NAFLD), but it is unclear whether it can reduce ...

Authors: Veera Houttu, J. Bouts, Y. Vali, J. Daams, A. Grefhorst, M. Nieuwdorp, A. G. Holleboom

Date Published: 21st Nov 2022

Journal: Front Endocrinol (Lausanne)

Tissue-wide metabolomics reveals wide impact of gut microbiota on mice metabolite composition.
WP4 - Big data analysis of the gut microbiome, WP7 - Dissemination, Exploitation and Communication

Abstract (Expand)

The essential role of gut microbiota in health and disease is well recognized, but the biochemical details that underlie the beneficial impact remain largely undefined. To maintain its stability, ...

Authors: I. Zarei, V. M. Koistinen, M. Kokla, A. Klavus, Ambrin Farizah Babu, M. Lehtonen, S. Auriola, K. Hanhineva

Date Published: 2nd Sep 2022

Journal: Sci Rep

Evaluation of Caco-2 and human intestinal epithelial cells as in vitro models of colonic and small intestinal integrity.
WP5 - Phenotyping, engineering and characterisation, WP7 - Dissemination, Exploitation and Communication

Abstract (Expand)

Although the colonic cell line Caco-2 is widely used as a model of the small intestinal barrier function, it has limitations such as overestimated transepithelial electrical resistance (TEER) compared ...

Authors: S. Lopez-Escalera, A. Wellejus

Date Published: 25th Jul 2022

Journal: Biochem Biophys Rep

Risk assessment with gut microbiome and metabolite markers in NAFLD development.
WP4 - Big data analysis of the gut microbiome, WP7 - Dissemination, Exploitation and Communication

Abstract (Expand)

A growing body of evidence suggests interplay between the gut microbiota and the pathogenesis of nonalcoholic fatty liver disease (NAFLD). However, the role of the gut microbiome in early detection of ...

Authors: Howell Leung, X. Long, Y. Ni, L. Qian, Manos Nychas, Sara Leal Siliceo, Dennis Pohl, K. Hanhineva, Y. Liu, A. Xu, H. B. Nielsen, E. Belda, K. Clement, R. Loomba, H. Li, W. Jia, G. Panagiotou

Date Published: 8th Jun 2022

Journal: Sci Transl Med

Effects of broad-spectrum antibiotics on the colonisation of probiotic yeast Saccharomyces boulardii in the murine gastrointestinal tract.
WP5 - Phenotyping, engineering and characterisation, WP7 - Dissemination, Exploitation and Communication

Abstract (Expand)

Mouse models are commonly used to study the colonisation profiles of microorganisms introduced to the gastrointestinal tract. Three commonly used mouse models include conventional, germ-free, and ...

Authors: Alex Hedin, V. E. Rees, H. Zhang, V. Kruse, R. Vazquez-Uribe, M. O. A. Sommer

Date Published: 25th May 2022

Journal: Sci Rep

Effects of exercise on NAFLD using non-targeted metabolomics in adipose tissue, plasma, urine, and stool.
WP7 - Dissemination, Exploitation and Communication

Abstract (Expand)

The mechanisms by which exercise benefits patients with non-alcoholic fatty liver disease (NAFLD), the most common liver disease worldwide, remain poorly understood. A non-targeted liquid chromatography-mass ...

Authors: Ambrin Farizah Babu, Susanne Csader, V. Mannisto, M. M. Tauriainen, H. Pentikainen, K. Savonen, A. Klavus, V. Koistinen, K. Hanhineva, Ursula Schwab

Date Published: 20th Apr 2022

Journal: Sci Rep

Identification and Distribution of Sterols, Bile Acids, and Acylcarnitines by LC-MS/MS in Humans, Mice, and Pigs-A Qualitative Analysis.
WP7 - Dissemination, Exploitation and Communication

Abstract (Expand)

Sterols, bile acids, and acylcarnitines are key players in human metabolism. Precise annotations of these metabolites with mass spectrometry analytics are challenging because of the presence of several ...

Authors: A. F. Babu, V. M. Koistinen, S. Turunen, G. Solano-Aguilar, J. F. Jr Urban, I. Zarei, K. Hanhineva

Date Published: 7th Jan 2022

Journal: Metabolites

Physical Activity and Dietary Composition Relate to Differences in Gut Microbial Patterns in a Multi-Ethnic Cohort-The HELIUS Study.
WP4 - Big data analysis of the gut microbiome, WP7 - Dissemination, Exploitation and Communication

Abstract (Expand)

Physical activity (PA) at recommended levels contributes to the prevention of non-communicable diseases, such as atherosclerotic cardiovascular disease (asCVD) and type 2 diabetes mellitus (T2DM). Since ...

Authors: Veera Houttu, Ulrika Boulund, M. Nicolaou, A. G. Holleboom, A. Grefhorst, H. Galenkamp, B. J. van den Born, K. Zwinderman, M. Nieuwdorp

Date Published: 9th Dec 2021

Journal: Metabolites

Positive Effects of Exercise Intervention without Weight Loss and Dietary Changes in NAFLD-Related Clinical Parameters: A Systematic Review and Meta-Analysis.
WP7 - Dissemination, Exploitation and Communication

Abstract (Expand)

One of the focuses of non-alcoholic fatty liver disease (NAFLD) treatment is exercise. Randomized controlled trials investigating the effects of exercise without dietary changes on NAFLD-related clinical ...

Authors: Ambrin Farizah Babu, Susanne Csader, Johnson Lok, C. Gomez-Gallego, K. Hanhineva, H. El-Nezami, Ursula Schwab

Date Published: 8th Sep 2021

Journal: Nutrients

Decreased Abundance of Akkermansia muciniphila Leads to the Impairment of Insulin Secretion and Glucose Homeostasis in Lean Type 2 Diabetes.
WP4 - Big data analysis of the gut microbiome

Abstract (Expand)

Although obesity occurs in most of the patients with type 2 diabetes (T2D), a fraction of patients with T2D are underweight or have normal weight. Several studies have linked the gut microbiome to ...

Authors: J. Zhang, Y. Ni, L. Qian, Q. Fang, T. Zheng, M. Zhang, Q. Gao, Y. Zhang, J. Ni, X. Hou, Y. Bao, P. Kovatcheva-Datchary, A. Xu, H. Li, G. Panagiotou, W. Jia

Date Published: 5th Jun 2021

Journal: Adv Sci (Weinh)

Powered by
Seek new full (v.1.8.3)
FAIRDOM | Funding and Programmes | Credits
Copyright © 2008 - 2019 The University of Manchester and HITS gGmbH